Figure 1.

Figure 1.

Leukocyte migration in response to acute injury is visualized in zebrafish embryo model (Tg:zlyz-EGFP). (a).Tg:zlyz-EGPF embryos (at 3dpf) were subjected with tail transection for generating zebrafish leukocyte migration model. The red line means the incision of tail transection, and the square region means the highly inflamed region. (b–c). Leukocytes that migrated to the highly inflamed regions [white boxes in (b)] in Tg:zlyz-EGFP embryos (3 dpf, n denotes the number of zebrafish embryos) with tail transection were quantitatively analyzed at different time points(c). (d). Schematic diagram of zebrafish leukocyte recruitment and resolution in acute inflammation.