Figure 1

Figure 1

Cancer cell proliferations were suppressed after 48-h drug treatment in the zebrafish xenotransplanted with human A549 non-small-cell lung cancer cells, human SGC-7901 stomach cancer cells, human HepG2 liver cancer cells, human JF 305 pancreatic cancer cells, and human MCF-7 breast cancer cells. a1, b1, c1, d1 and e1 were the control xenotransplanted zebrafish without drug treatment. a2–a6 were treated with Bevacizumab, cis-Platinum, Endostar, Paclitaxel and Vinorelbine; b2–b6 were treated with 5-FU, Hydroxyurea, cis-Platinum, Irinotecan and Paclitaxel; c2–c6 were treated with Adriamycin, Gemcitabine, Hydroxyurea, cis-Platinum and 5-FU; and d2–d4 as well as e2–e4 were treated with Furanodiene at concentrations of 1/9 MTC, 1/3 MTC and MTC, respectively. A representative entire body of the xenotransplanted zebrafish body was shown in f.