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Fig. 1
csf1r CRISPants phenocopy existing csf1r microglia mutants. (A) Neutral Red (NR+) images and quantification of wild-type (WT), csf1ra−/− and csf1ra CRISPant zebrafish larvae at 3 dpf. (B) Indel spectrum of a pool of csf1ra CRISPants calculated by TIDE. (C) NR images and quantification of WT and spi1b CRISPant zebrafish larvae at 3 dpf. (D) Indel spectrum of a representative individual spi1b CRISPant calculated by TIDE. The R2 value represents reliability of the indel spectrum. ***P<0.001. One-way ANOVA and Student's t-test. Each dot represents one larva. Error bars represent s.d.
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