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Dohn et al., 2019 - Nr2f-dependent allocation of ventricular cardiomyocyte and pharyngeal muscle progenitors

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Fig. 6

Nr2f1a; nr2f2 mutants have deficiencies in their posterior PMs.

(A-D) PMs in nr2f1a^wt; nr2f2^wt, nr2f1a^mut; nr2f2^wt, nr2f1a^mut; nr2f2^het, and nr2f1a^mut; nr2f2^mut embryos with the actc1b:GFP transgene at 96 hpf. IHC was performed for GFP. Views are lateral with anterior to the left and dorsal up. Arrows in C and D indicate largely absent protractor pectoralis (pp). Brackets in C and D indicate 1^st and 2^nd arch PMs. ah–adductor hyoideus, ao–adductor operculi, do–dilator operculi, lap–levator arcus palitini. Muscle nomenclature used is from [55]. (E) Percentage of nr2f1a^ctrl; nr2f2^ctrl (n = 18), nr2f1a^mut; nr2f2^wt (n = 10), nr2f1a^mut; nr2f2^het (n = 29), and nr2f1a^mut;nr2f2^mut (n = 15) embryos with loss or malformed pp muscles at 96 hpf.

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