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Fig. 2-S1
Categorization of β-cells based on their mantle/core localization in the islet.
(A) Representative z-stack images of β-cells in a live Tg (ins:Rcamp1.07) zebrafish embryo at 72 hpf. Red solid circles mark β-cells in the islet core determined in the current focal plane; red dotted circles mark β-cells in the islet core determined in other focal planes. (B) 3D-projection of the islet showed in (A). The inset describes an illustration of β-cells in the mantle (green) and β-cells in the core (yellow to red) of the islet. Scale bars: 10 μm; scale bars apply to (A–B).
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