Sensory neurite development in the caudal fin of sensory:GFP embryos at different timepoints. Sensory neurite development in the caudal fin of sensory:GFP embryos was followed at several stages of development (24, 36, 48, and 56 hpf). Indicated by the red frame is the developmental stage (48 hpf) that was used to study the effect of the pathogenic p.(I228M) and p.(G856D) mutations. Images represent maximal projections of confocal recordings at 20× magnification. Scale bar indicates 100 μm.