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Fig. 4

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Publication: Ramanagoudr-Bhojappa et al., 2018 - Multiplexed CRISPR/Cas9-mediated knockout of 19 Fanconi anemia pathway genes in zebrafish revealed their roles in growth, sexual development and fertility
All Figures: Figures for Ramanagoudr-Bhojappa et al., 2018

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Figure Caption

Fig. 4 Homozygous fancp mutants are significantly smaller in body length than their siblings.

Standard length measurements of fancp fish at 1 mpf (A), and 4 mpf (B). (i) Number of fish genotyped and measured for both fancp alleles: hg66 and hg67. (ii) Representative images of fancp^+/+ and fancp^hg66/hg66 fish with red arrows marking the beginning of caudal fin used in length measurements. (iii) Data on body size measurements for fancp^+/+, fancp^hg66/+ and fancp^hg66/hg66 fish. Both time points show a significant decrease in size of fancp^hg66/hg66 fish compared to the WT and heterozygous clutch mates (ANOVA analysis, ***p<0.001). Data for fancp_hg67 is shown in S8 Fig.

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Phenotype details

Acknowledgments

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