ZFIN Image: Zhang et al., 2018, Fig. S4

Image

Figure Caption

Fig. S4

hrg1 DKO zebrafish undergoes normal erythrophagocytosis with defects in heme-iron recycling.

(A) Perl’s Prussian blue iron staining of kidney sections from Tü and hrg1 DKO zebrafish with control (non-PHZ), 1 day, 2 days and 3 days post PHZ-treatment. Yellow arrows: macrophages. (B) DAB-enhanced perl’s iron staining of spleen sections from Tü and hrg1 DKO zebrafish with control (non-PHZ), 1 day, 2 days and 3 days post PHZ-treatment. (C) IHC staining of Hrg1 proteins in kidney, spleen and liver of adult hrg1 DKO zebrafish sections. (D) H&E staining of kidney, spleen and liver sections from hrg1 DKO zebrafish with control (non-PHZ) and 1-day post PHZ-treatment. Scale bar: 20μm.

Acknowledgments

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