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Fig. 2
lrba is expressed in the gut but it is not required for ENS development in zebrafish. (A) In situ hybridization performed in zebrafish embryos showed the expression pattern of lrba during embryonic development. At 24 hpf, lrba is present along the yolk sack and is weakly expressed in the hindbrain. This pattern of expression is detected throughout all time points analyzed. From 72 hpf, a strong signal is detected in the intestinal bulb (arrows). (B) HuC/Elavl3 staining showed that the distribution and number of enteric neurons along the gut in lrba morphants is similar to controls.
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