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Fig. 1-S1
BMP signaling inhibition at bud stage medializes tail mesoderm.
Transgenic fli1:gfp embryos were heat-shocked at the bud stage. Embryos that also had the HS:dnbmpr transgene exhibited a loss of endothelium and gain of somite tissue compared to control embryos (B compared to A). Similarly, kdrl:GFP embryos treated with the BMP inhibitor DMH1 showed a loss of endothelium and expansion of ectopic somite tissue compared to DMSO-treated control embryos (D compared to C).
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