ZFIN Image: Yang et al., 2018, Fig. 3

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Figure Caption

Fig. 3

UVRAG is required for melanocyte development in zebrafish in vivo. (A) Representative images of 48 h postfertilization (hpf) zebrafish embryos injected with control morpholino (MO) or MO targeting uvrag, pmel, or tyr. Rescue of uvrag MO-mediated depigmentation is shown by coinjection of human uvrag mRNA. Box highlights area of enlargement visualized in Insets. Numbers on each panel indicate the number of embryos showing the representative phenotype per total number of embryos examined. (B) Quantitative measurement shows significantly decreased pigmentation in uvrag MO and pmel MO group compared with the control group. Means were calculated from the data collected from three independent experiments (n = 50). ***P < 0.001; ****P < 0.0001.

Figure Data

Phenotype details

Acknowledgments

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