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Fig. S4
sec23b-/- ZF histology and GFP expression of ZF injected with a vector (designed to integrate into the ZF genome) expressing Sec23a and GFP from a ubiquitin promoter.
(A) sec23b-/- ZF exhibit normal pancreas histology at day 16 and (B) normal staining with o-dianisidine at day 7 compared to WT clutchmate controls. (C) The sec23a cDNA is expressed from a ubiquitin promoter with a P2A sequence separating it from a sequence encoding GFP. (D) Ubiquitous Sec23A expression (approximated by GFP), as expected from vector integration into onecell stage embryos.
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Full text @ Proc. Natl. Acad. Sci. USA