Fig. 6
Effect of Ifng1-2 on the activation of immune cells and on survival against Spring Viremia Carp Virus (SVCV). (A) Zebrafish larvae overexpressing ifng1-2 show the activation of macrophages and neutrophils, with an evident change in morphology from a spherical morphology to a dendritic morphology. (B) Kaplan–Meier survival curves after SVCV challenge in zebrafish larvae overexpressing or not overexpressing ifng1-2 (C) Kaplan–Meier survival curves after SVCV challenge in adult zebrafish co-inoculated or not co-inoculated with the Ifng1-2 recombinant protein. Significant differences are represented by asterisks (*p < 0.05).