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Fig. 3
Histopathology of adult npc1m/m liver and brain tissue. (A,B) Photographs of Hematoxylin and Eosin (H&E)-stained hindbrain tissue sections from adult npc1+/+ (A) and npc1m/m (B) zebrafish at 9 weeks of age. Axonal spheroids are indicated by the arrowheads. Scale bar: 50 μm. (C,D) H&E-stained cerebellar sections from 9-week npc1+/+ (C) and npc1m/m (D) zebrafish. The arrows indicate cerebellar Purkinje neurons. Scale bar: 100 μm. (E,F) H&E-stained liver sections from 9-week npc1+/+ (E) and npc1m/m (F) zebrafish. Scale bar: 50 μm.
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