ZFIN Image: Ferrero et al., 2018, Fig. 5

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Figure Caption

Fig. 5

The Transcription Factor cmyb Is Required for the Establishment of Adult MG

(A) Scheme of the hematopoietic cell transplantation experiments performed to circumvent the lethality of c-myb^null animals due to the lack of definitive hematopoiesis.

(B) GFP immunostaining performed on adult brain sections from wild-type controls (upper panels) and rescued cmyb^null mutants (lower panels), demonstrating a complete absence of host-derived GFP⁺ MG in the cmyb mutants (left panels), as well as the presence of GFP⁻ donor-derived L-plastin⁺ hematopoietic cells (fuchsia, middle panels). The right panels show a merge of both fluorescent channels (n = 4). Scale bar: 50 μm.

Acknowledgments

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