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Fig. S1
Cellular localization of α-SMA, Tgfb and Serotonin. 3-dpf kras+ larvae were treated with dox for 4 days and IF staining was carried out for α-SMA (A) Tgfb (B) and serotonin (C). Representative images of liver sections are shown. GFP signals were derived from GFP-Kras fusion protein in kras+ fish and are mainly in hepatocyte membrane and cortex region as we previously reported (reference 16). DAPI was count-stained for visualization of nuclei. Boxed regions are enlarged as insets in the left-bottom corners. Scale bar, 10 μm.
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