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Fig. S5
- ID
- ZDB-IMAGE-180706-10
- Publication
- Siddam et al., 2018 - The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development
- All Figures
- Figures for Siddam et al., 2018
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Figure Caption
Fig. S5
celf1 deficiency results in ocular defects in zebrafish and Xenopus laevis.
(A) celf1 knockdown (KD) in zebrafish results in microphthalmia and clouding of the eye by 4dpf. (B and C) Histological analysis of X. laevis morphants at St. 42. celf1-knockdown (morpholino injected side) shows various eye defects such as (B) small eye and (C) skewed eye, that are absent in the control uninjected side. (D) Graph representing the distribution of the observed eye defects in X. laevis celf1 morphants from three independent experiments.
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