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Fig. 2
Cell death is not required for choroid fissure fusion. Images of whole eyes (A?B') or Z-stacks of the retina (C?C') of wildtype (left column) and NO067 mutant (right column) embryos at ages shown bottom right. Arrows show position of the choroid fissure. (A?B') TUNEL labeling (blue) of dying cells. There are more apoptotic cells in the mutant eye but they do not localize to the choroid fissure. (C?C') DAPI staining of nuclei showing the retina of the mutant eye has undergone normal morphogenesis in the absence of macrophages. Scale bar: 50 ?M.
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Full text @ Front. Cell. Neurosci.