ZFIN Image: Vopalensky et al., 2018, Fig. 3

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Figure Caption

Fig. 3

Increasing the level of oep mRNA prolongs the window of responsiveness to Nodal. (A) Time series of oep expression. (B) Intercellular injection of Activin A induces ectopic ntl expression in the animal cap at 50%, shield and 75% epiboly. (C) In oep-injected embryos, but not egfp-injected control embryos, rhNodal is able to induce ectopic ntl at 75% epiboly. (D) Box plot showing the fraction of embryos with ectopic ntl expression (based on data shown in C). The number of embryos with the indicated expression among the total number examined in experiments performed in duplicate (B) or triplicate (C) is indicated. All side views are shown with dorsal towards the right. Scale bar: 250 µm.

Acknowledgments

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