Fig. 5
Retinal development following il7r knockout.
a-d HE staining and magnified images of retinas from wild-type (WT, a and b) and il7r?/? (c and d) embryos at 72 hpf. e?h Images of Zpr1 or Zpr3 immunofluorescence staining of retinas in WT (e and f) and il7r?/? (g and h) embryos at 72 hpf. i-j Statistical analysis of Zpr1-positive signals (i) and Zpr3-positive signals (j) between WT and il7r?/? retinas. Note that the Zpr1-positive area (i) and Zpr3-positive area (j) are significantly decreased in il7r?/? retinas. Results are represented as means?±?SEM (n?=?10), **P?<?0.01, ***P?<?0.001. Scale bar: a and c, 40??m; b and d, 10??m; e?h, 50??m. GCL ganglion cell layer, INL inner nuclear layer, ONL outer nuclear layer, ON optic nerve