ZFIN Image: Aguillon et al., 2018, Fig. 1

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Fig. 1

Islet1/2 labels Gnrh3 neurons of the olfactory epithelium and its expression is unaffected in sox10 mutants.

(A) Single confocal sections of olfactory epithelia from Tg(gnrh3:eGFP) embryos at 48 hpf, in either wildtype or sox10^t3/t3 mutants, labelled for the expression of Islet1/2 (magenta) and eGFP (green); nuclei are labelled with DAPI (grey). Embryos are viewed dorsally and the inset in the first panel shows a schematic representation of a 48 hpf embryonic head indicating the region analysed. Dotted lines highlight the olfactory epithelia and scalebars represent 15 μm. (B) Counts of cells expressing Islet1/2 in either wildtype or sox10^t3/t3 mutant epithelia (6.8 ± 0.3 versus 6.9 ± 0.4 cells per epithelium, n = 16 epithelia). (C) Counts of cells expressing eGFP from the Tg(gnrh3:eGFP) transgene in either wildtype or sox10^t3/t3 mutant placodes (7.2 ± 0.3 versus 7.1 ± 0.4 cells per epithelium, n = 16 epithelia). (B–C) Mean ±s.e.m. P values are calculated using a two-tailed Student's t-test, n.s. not significant.

Acknowledgments

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