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Fig. S6
Jarid2 over-expression inhibits vascular development.
A, Tube formation assay using HUVEC cells following transfection with the vector and Jarid2 constructs, respectively. White arrow indicates the defective tube formation B, Quantitative analysis of the number of vascular tubes per field at 10x magnigfication. Note the decreased number of tubes following over-expression of Jarid2. C, Quantitative analysis of tube formation following co-injection of Jarid2 and miR-130a mimics. Note the restoration of tube formation upon co-expression of Jarid2 and miR-130a mimics. Error bars indicate SEM (*p<0.05).
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