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Fig. 4
Histopathological examination of the kidney marrow, spleen and liver of spi1:SOCS1-2A-mCherry or SOCS1/FLT3-ITD double transgenic fish. (a and b) Hematoxylin and eosin stains of the kidney marrow, spleen and liver from 9- and 12-month old spi1:SOCS1-2A-mCherry transgenic, SOCS1/FLT3-ITD double transgenic and wild-type fish. Kidney marrows from spi1:SOCS1-2A-mCherry transgenic or SOCS1/FLT3-ITD double transgenic fish show increased infiltration by myeloid cells compared with wild-type fish.
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