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Fig. 2
Effect of inhibition of Wnt signaling pathway on krasV12- and Myc-induced liver enlargement.
7?dpf fabp10+, kras+ or Myc+ larvae were treated with either 10??M IWR1 or 10??M Cardionogen 1 in the presence of 10??g/ml Dox and 2D liver size was measured based on images. (A?C) Representative images of 7?dpf fabp10+ control larvae. (D?F) Representative images of 7?dpf kras+ larvae. (G?I) Representative images of 7?dpf Myc+ larvae. (J) Quantification of liver sizes for kras+ larvae. (K) Quantification of liver sizes for Myc+ larvae. N?=?20 from each groups; statistical significance: *p?<?0.05, Scale bar?=?20??m.
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