IMAGE

Fig. S5

ID: ZDB-IMAGE-171228-3
Publication: Kuo et al., 2016 - PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress
All Figures: Figures for Kuo et al., 2016

Image

Figure Caption

Fig. S5

Morpholino (MO) knockdown of pycr in zebrafish affects somatogenesis and cerebral hemorrhage during embryonic stages. (A) Each pycr MO (7.5 ng) was injected into wild-type zebrafish embryos at the 1- to 2-cell stage and evaluated at 48 hours post fertilization (hpf). The major defects of pycr1-morphants (left panel) or pycr3-morphants (right panel) were reduced body length and a curly tail. The pycr2-MO injected embryos exhibited no obvious abnormality, but the morphants shows cerebral hemorrhage (middle panel). Arrows indicate area of hemorrhage. Lateral views of representative wild-type control (Ctrl) or MO-injected fish were photographed at 48 hpf. Bar: 100 µm. (B) Phenotypic distributions of pycr1, pycr2 and pycr3 morphants.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.