Fig. 7
DL caudal compaction regulates proximal tubule proliferation and segment size.
(A) Top panels show low magnification lateral views of the same embryo labelled with Hnf1b. Asterix denotes the site of ablation. Bottom panels show close-up views of the highlighted region of the ablated and contralateral control side of the embryo. (B) Histogram of the percentage of Hnf1b nuclei that are EdU+ in the control non-ablated side and ablated side of the tubule in 6 embryos. (C) Panels show lateral views of 24 hpf embryos treated with LY294002 or DMSO (control) and labelled with EdU from the 12-somite stage to 24 hpf. (D) Histogram of the percentage of Hnf1b nuclei that are EdU+ in control and LY294002 treated embryos.