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Fig. 5
Lipid accumulation in larvae treated with VPA and TSA.
Oil Red O staining shows the localization of neutral lipids in 10 dpf larvae that have been on a high fat diet between 6 dpf and 9 dpf. An arrow indicates the liver. Control embryos (a-c), embryos treated with increasing concentrations of TSA (d-u) or VPA (A-L). The red lozenges on the right schematize the lipid accumulation, highlighting the non-monotonic dose response. Note that the maximum accumulation is observed at intermediate concentrations.
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