Fig. S2
ASO-mediated RNA knockdown is applicable to multiple different transcripts.
A) Summary quantitation of survival and phenotypes of ASO-injected embryos at 24 hpf. Percentage plots are derived from multiple independent experiments (at least 2 independent experiments per ASO). Compiled numbers of embryos scored for each ASO are indicated. B) Representative images of smad2 ASO (left) and ntla ASO (right)-injected embryos at 30 hpf. ntla ASO caused a gene-specific phenotype only in a subset of embryos (left: overview image with phenotypic and non-phenotypic embryos; right: higher magnification view of phenotypic embryos).