ZFIN Image: Paatero et al., 2017, Fig. 3

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Figure Caption

Fig. 3

Dechorionation sensitizes embryos for MSN induced toxicity. (A) Images of dechorionated zebrafish embryos at 96 hpf after treatment with NH2. PEI, SUCC and PEG.-MSNs. The treatment was initated at 24hpf. (B–E) Percentage of survival of dechorionated embryos at 48 hpf, 72hpf and 96 hpf upon treatment with (B) NH2, (C) PEI, (D) SUCC and (E) PEG MSNs at denoted concentrations. The treatment was initated at 24hpf. N = 24 embryos/treatment, except in PEI-MSN 0 μg/ml (n = 25), SUCC-MSN 0 μg/ml (n = 23), SUCC-MSN 10 μg/ml (n = 23) and SUCC-MSN 100 μg/ml (n = 25). Each embryo was followed throughout the experiment and score live or dead on each day (F) Comparison of survival between MSNs at 100 μg/ml concentration.

Acknowledgments

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