Fig. S1
miR-27 is a highly conserved miRNA with enriched expression in the pharyngeal arches. (A) Alignment of the zebrafish miR-27a-e sequences by ClustalW2, with conserved regions highlighted in blue and indicated with stars. (B) Alignment of miR-27a sequences from human (hsa), mouse (mmu), xtr (Xenopus), and dre (zebrafish). (C) miR-27a expression in embryos between 24 hpf to 72 hpf, detected by whole-mount in situ hybridization. Expression of miR-27a (D), miR-27b (E), miR-27c (F), in 4dpf embryos detected by whole-mount in situ hybridization. Lateral views with images on the right are closed up views of the head.
Reprinted from Developmental Biology, 429(1), Kara, N., Wei, C., Commanday, A.C., Patton, J.G., miR-27 regulates chondrogenesis by suppressing Focal Adhesion Kinase during pharyngeal arch development, 321-334, Copyright (2017) with permission from Elsevier. Full text @ Dev. Biol.