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Fig. S5
Embryos lacking endoderm fail to undergo endocardial migration and display disorganized heart tubes. (A-B) Snapshots of epifluorescence time-lapse movies of control or sox32 MO-injected Tg(fli:EGFP) embryos at the indicated stages (supplementary movie 3). White arrowheads: endocardial precursors. (C-D) Confocal Z-stack images of 28-hpf Tg(myl7:mCherry/fli:EGFP) embryos, showing myocardium (magenta) and endocardium (green). White arrowheads: endocardium located at the outer layer. Dorsoanterior view with anterior up.
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Reprinted from Developmental Biology, 414, Xie, H., Ye, D., Sepich, D., Lin, F., S1pr2/Gα13 signaling regulates the migration of endocardial precursors by controlling endoderm convergence, 228-43, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.