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Fig. 2
WHS related phenotypes in whsc1−/− zebrafish. (A) Brain morphology in whsc1−/− and wild-type embryos. Arrow heads point to the diencephalic ventricle (homologue of mammalian third ventricle). (B) Motor neuron development in whsc1−/− and wild-type embryos. Note that the number of motor neurons in whsc1−/− mutant larva was significantly less than that in wild-type ones. (C) whsc1−/− adult zebrafish showed heart enlargement. (D) Tissue section analysis of the heart of wild-type or mutant adult fishes. Arrows point to the hearts. (E) Statistics of heart enlargement in these two mutation lines.
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