ZFIN Image: Meda et al., 2016, Fig. S1

Image

Figure Caption

Fig. S1

Sox10 and Shh are activated shortly after lesion. Immunofluorescence staining for immature SC marker, Sox10 (white), Shh-expressing cells (anti-GFP, Shh:GFP fish) (green), and the axonal marker, acetylated tubulin (red). A lesion was performed in between the rays. As soon as 0.25 hpl, Sox10-positive and Shhexpressing cells are detected surrounding the lesion. Once the wound is healed (3 hpl), Shh-expressing cells are no longer detectable, whereas several Sox10-positive cells continue to set along the wound. Scale bars = 50 µM. Dotted lines represent the hole generated by the lesion. GFP, green fluorescent protein; hpl, hours postlesion; SC, Schwann cell.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Antioxid. Redox Signal.