ZFIN Image: Wang et al., 2016, Fig. S6

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Figure Caption

Fig. S6

Blocking the function of MEK with specific inhibitor U0126 or PD98059 treatment resulted in sprouting angiogenesis defects. A. Confocal images of ISVs morphology in 30 hpf Tg(kdrl:EGFP) transgenic embryos treated with DMSO, U0126 or PD98059. B. Confocal images of 30hpf Tg(fli1a:EGFP) transgenic embryos treated with DMSO, U0126 or PD98059. C. The statistics of ISV length in embryos treated with DMSO, U0126 or PD98059. One-Way ANOVA; ***,P<0.001. D. Quantification of ECs nuclei number in ISV. Measurements were made from three adjacent ISVs (over yolk) per embryo from 3 independent experiments. One-Way ANOVA; ***, P<0.001.

Acknowledgments

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