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Fig. S4
The migratory NCC population is not undergoing apoptosis in polr1c and polr1d mutant embryos.
(A-D) TUNEL staining in sox10:gfp embryos shows increased cell death in mutant embryos which does not co-localize with the migratory NCC population. At 24 hpf, increased cell death can be seen in the neuroepithelial region of polr1c-/- and polr1d-/- embryos. (E-F) At 48 hpf, increased cell death can be observed in regions of the brain and eye of mutant embryos, but not within the pharyngeal arches. Scale bar = 200 μm.
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