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Fig. S6
Inhibition of RhoA affects remodeling of the furrow microtubule array. Embryos were injected with RhoA inhibitor (Rhosin) at one cell stage and at 8-cell inmunolocalization of α-tubulin was performed. (A and B) At 8 cell embryonic stage microtubules from injected embryos with Rhosin are disorganized at the cleavage furrow (n=6) compared to the buffer injected embryos (n=6) where the microtubules showed a perpendicular distribution towards the cleavage furrow in 3 independent experiments.
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Reprinted from Developmental Biology, 421(1), Miranda-Rodríguez, J.R., Salas-Vidal, E., Lomelí, H., Zurita, M., Schnabel, D., RhoA/ROCK pathway activity is essential for the correct localization of the germ plasm mRNAs in zebrafish embryos, 27-42, Copyright (2017) with permission from Elsevier. Full text @ Dev. Biol.