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Fig. S2
C3 affects the localization of active RhoA at the cleavage furrow. (A and B) Active RhoA was immunolocalized with an anti-active-RhoA (RhoA-GTP) mouse monoclonal antibody and visualized by confocal microscopy. (A) Embryos were injected with control buffer (n=24) or with (B) C3 (n=30). a1 and a2 show magnification of regions highlighted in A. b1 and b2 show magnification of regions highlighted in B.
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Reprinted from Developmental Biology, 421(1), Miranda-Rodríguez, J.R., Salas-Vidal, E., Lomelí, H., Zurita, M., Schnabel, D., RhoA/ROCK pathway activity is essential for the correct localization of the germ plasm mRNAs in zebrafish embryos, 27-42, Copyright (2017) with permission from Elsevier. Full text @ Dev. Biol.