ZFIN Image: Xiao et al., 2016, Fig. S8

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Figure Caption

Fig. S8

Inhibition of brg1 impairs cardiac regeneration. (a-c) BrdU⁺/Mef2C⁺ proliferating cardiomyocyte were comparable between wt sibling hearts (a) and dn-xBrg1 transgenic hearts (b) at 14 dpa without heat shock treatment [(-) HS]. (c) Percentages of BrdU⁺/Mef2C⁺ cardiomyocytes in the injured area. (d-f) PCNA⁺/ Mef2C⁺ proliferating cardiomyocytes (arrowheads) decreased in dn-xBrg1 tg hearts (e) compared with wt sibling hearts (d) at 14 dpa with heat shock treatment. (f) Quantification of cardiomyocyte proliferation assessed by PCNA⁺/ Mef2C⁺ staining Scale bars, 100 μm. Data presented are mean ± s.e.m.; paired Student’s t-test, sample numbers are listed under each group, ** p < 0.01.

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