ZFIN Image: Kantarci et al., 2016, Fig. S5

Image

Figure Caption

Fig. S5

Effects of altering gsc function on ZO-1 and p-Paxillin. (A–I) Cross-sections through the neurogenic domain just posterior to the utricular macula in a control embryo (A, D, and G), gsc mutant (B, E, and H) and hs:gsc embryo (C, F, and I) at 24 hpf. These are the same sections depicted in Fig. 2 K–P but showing costaining for p-Paxillin (red) and ZO-1 (green) (A–C) or ZO-1 alone (D–I). The boxed regions in A–F are enlarged in G–I. White arrows (A–C) indicate cells undergoing EMT with elevated basal accumulation of p-Paxillin, whereas double-headed arrows (D–I) span the otic epithelium to highlight changes in ZO-1 staining.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA