ZFIN Image: Shin et al., 2016, Fig. S3

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Figure Caption

Fig. S3

SL327 treatment blocks Vegfa-induced expansion of flt4 and dll4. (A-C) Whole mount in situ hybridization of embryos fixed at 27 hpf using riboprobes against (A) kdrl, (B) flt4, or (C) dll4. Embryos were injected with indicated mRNA encoding either mCherry or Vegfa₁₂₁ followed by treatment from 23 to 27 hpf with the indicated compound. Numbers of embryos with representative phenotype are indicated in the lower right hand corner of each panel. Upper left panel, dorsal aorta (DA) and posterior cardinal vein (PCV) are indicated by brackets. Panels in second column, bracket denotes expanded expression of kdrl, flt4 and dll4 in both DA and PCV.

Acknowledgments

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