ZFIN Image: Marín-Juez et al., 2016, Fig. 3

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Figure Caption

Fig. 3

Induction of dn-vegfaa expression blocks revascularization of the damaged area. (A) Tg(hsp70l:dn-vegfaa);Tg(etv2:EGFP) ventricle at 40 hpi (n = 5). (A′) Inset shows high-magnification image of the injured area. (B) Tg(etv2:EGFP) WT ventricle at 40 hpi (n = 5). (C) Tg(etv2:EGFP) WT ventricle at 4 dpi (n = 5). (D) Tg(hsp70l:dn-vegfaa);Tg(etv2:EGFP) heart at 4 dpi (n = 3). White arrowheads point to coronary vessels sprouting into the injured area; yellow arrows point to disconnected endothelial cells; asterisk mark an area of coronary plexus. Dotted lines delineate the injured area. AVC, atrioventricular canal; BA, bulbus arteriosus. (Scale bar: 100 µm.)

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA