IMAGE

Fig. 2

ID

ZDB-IMAGE-160824-35

Genes

EGFP

Antibodies

zn-5

Publication

Bräutigam et al., 2011 - Vertebrate-specific glutaredoxin is essential for brain development

All Figures

Figures for Bräutigam et al., 2011

Image

Figure Caption

Fig. 2

Knockdown of zfGrx2 suppressed formation of a neuronal network. Morpholino-induced knockdown of zfGrx2 led to loss of early HuC/D positive neurons between 22 and 24 hpf (A). As demonstrated by different techniques, all tested neuronal subgroups were affected at 24 hpf: glutamatergic excitatory interneurons, dopaminergic neurons, and secondary motor neurons (B). Embryos lacking zfGrx2 were not able to develop an axonal scaffold (C). Ac, anterior commissure; dlt, dorsal longitudinal tract; nMLF, nucleus of the medial longitudinal fascicle; poc, posterior commissure; tg, trigeminal ganglion; vlt, ventral longitudinal tract. Scale bar, 50 µm.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA