ZFIN Image: Stawicki et al., 2016, Fig. 5

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Figure Caption

Fig. 5

Intraflagellar transport (IFT) but not transition zone mutants show defects in kinocilia morphology. Neuromasts of 5 dpf zebrafish larvae stained with acetylated tubulin to label kinocilia. (A) Mutations in the IFT genes dync2h1, wdr35, ift88, and traf3ip cause a lack of kinocilia in cells. A mutation in the ciliary axoneme gene arl13b causes a shortening, but not an absence, of kinocilia. (B) Kinocilia morphology appears unchanged by mutations in the transition zone genes cc2d2a, mks1, and cep290. Images to the far left are of representative wild-type sibling. No differences were observed among siblings of the different mutants. Scale bar = 10 µm. Mut, mutant; WT Sib, wild-type sibling.

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Acknowledgments

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