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Raman et al., 2016 - aPKC regulates apical localization of Lgl to restrict elongation of microridges in developing zebrafish epidermis

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Fig. 2

The levels of apical Lgl increase in the apical domain of the head peridermal cells in has/apkc mutants.Immunostaining using anti-Lgl2 and E-cadherin antibodies (a) in wild-type and has/apkc mutant embryos. Immuno-colocalization of Lgl and F-actin in the apical domain of wild-type and has/apkc mutant embryos at 48 hpf (b). Colocalization coefficient analysis between Lgl and F-actin by Pearson’s (PC) method and Manders’ overlap for Lgl with F-actin (M1) and F-actin with Lgl (M2) at 48 hpf in wild-type and has/apkc mutant embryos (c). Asterisks in c indicate significant difference at P<0.001 by Student’s t-test. Scale bar in a and b is equivalent to 10 µm.

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This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.