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Fig. 2
Inhibition of HH signaling rescues liver morphology in DNA hypomethylated larvae. Cytokeratin-18 (green) labels biliary ducts. DNA methyltransferase (dnmt1) morphants show complete abrogation of biliary structure (B). Incubation of larvae in cyclopamine protects against liver degeneration (C). Numbers represent total livers with normal structure. A′-C′ diagram ductular structure of panels A-C, respectively.
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