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Fig. 1
Optimization of SchB concentration for treating zebrafish larvae.The gross morphology of zebrafish larvae under different treatment schemes from 3 to 8 dpf. (A-C) untreated controls; (D-F) larvae exposed to the same volume of DMSO carrier as in the 1.875 µM SchB treatment; (G-I) larvae exposed to 1.875 µM SchB; (J-K) larvae exposed to 3.75 µM SchB. In each treatment group, the lateral view of a representative larva at 3, 6 and 8 dpf is shown. Larvae exposed to higher SchB concentrations, including 7.5 and 15 µM, died relatively rapidly (Table 1); hence, these samples are not shown here. Scale bar = 200 µm.
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