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Fig. S3
Tubule dilation in mnx2b-morphants is independent of cardiac defects. Injections of a second mnx2b directed morpholino (MOmnr2b). (A) Proximal tubule dilation is very similar to mnx2b-MO injected embryo. (B-D) The change in kidney formation is independent of heart defects, as heart-beat rate was unaffected (B) and no heart edema were observed in mnx2b morphants (C, D). Shown are bright field (left) und GFP images of corresponding Tg(-8cldnb.1:lynEGFP)zf106 embryos.
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Reprinted from Developmental Biology, 411(1), Ott, E., Wendik, B., Srivastava, M., Pacho, F., Töchterle, S., Salvenmoser, W., Meyer, D., Pronephric tubule morphogenesis in zebrafish depends on Mnx mediated repression of irx1b within the intermediate mesoderm, 101-14, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.