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Fig. S9
insaMO does not increase β cell proliferation. (A-B′′) Merged and single channel confocal projections of 1 dpf control (A-A′′; n=6) and insaMO-injected (B-B′′; n=5) Tg(ins:CFP-NTR) islets stained with CFP (β cells, green), phospho-Histone H3 (red), and insulin (white). (C-D′′) Merged and single channel confocal planes of 1 dpf control (C-C′′; n=6) and insaMO-injected (D-D′′; n=5) Tg(ins:CFP-NTR) islets stained with CFP (β cells, green), EdU (red) and Insulin (white).
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Reprinted from Developmental Biology, 409(2), Ye, L., Robertson, M.A., Mastracci, T.L., Anderson, R.M., An insulin signaling feedback loop regulates pancreas progenitor cell differentiation during islet development and regeneration, 354-69, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.