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Fig. 9
Normal ex vivo epicardial regeneration in cav1 mutants. (A) Adult hearts of tcf21:NTR; tcf21:nucEGFP fish in different cav1 backgrounds were cultured as explants and tested for epicardial cell regeneration after at least 90% genetic ablation. White dashed lines delineate ventricles and red dashed lines delineate the epicardial sheet edge. Red arrows indicate the direction of epicardial regeneration. (B) Quantification of days to repopulate the ventricle after 90% or greater epicardial cell ablation. Mean±s.d., Student′s t-test; n=18 for wild type, n=26 for heterozygotes and n=21 for homozygotes. dpi, days post Mtz incubation.