ZFIN Image: Karra et al., 2015, Fig. 2

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Figure Caption

Fig. 2

NF-_KB is required for heart regeneration. (A) Schematic of βact2:RS-I_KBSR transgene. (B and C) Section images of cmlc2:CreER; βact2:RS-IκBSR; NF-_KB:eGFP hearts 60 d after treatment (dpt) with vehicle (n = 12) or 4-HT (n = 12). (D and E) Section images of cmlc2:CreER; βact2:RS-I_KBSR ventricles at 30 d after amputation after treatment with vehicle or 4-HT. Images are stained for troponin to denote cardiac muscle. Dashed line indicates approximate resection plane. (F and G). Section images of cmlc2:CreER; βact2:RS-I_KBSR ventricles at 30 d after amputation after treatment with vehicle or 4-HT. Images are stained with acid fuchsin orange G (AFOG) to identify scar (blue) and fibrin (red). (Scale bars: 100 µm.)

Acknowledgments

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